发明名称 TFPI INHIBITORS AND METHODS OF USE
摘要 The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, treat a blood coagulation disorder in a subject, purify TFPI, and identify a TFPI-binding compound.
申请公布号 US2013259863(A1) 申请公布日期 2013.10.03
申请号 US201313846359 申请日期 2013.03.18
申请人 BAXTER HEALTHCARE SA;BAXTER INTERNATIONAL INC. 发明人 DOCKAL MICHAEL;HARTMANN RUDOLF;FRIES MARKUS;SCHEIFLINGER FRIEDRICH;EHRLICH HARTMUT;REINEKE ULRICH;OSTERKAMP FRANK;POLAKOWSKI THOMAS
分类号 C07K14/00 主分类号 C07K14/00
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