发明名称 |
THE NEW DERIVATIVES OF (Z)-1,2-DIPHENYLETHENE |
摘要 |
The present invention relates to the new chemical compounds containing (Z)-1,2- diphenylethene moiety in the structures, particularly the new derivatives of cis-stilbene, the new derivatives of 4,5-diphenyl-1,3-oxazole, the new derivatives of 1-methyl-4,5-diphenyl-1H-imidazole and pharmaceutically acceptable salts thereof. The invention relates also to the application of aforementioned compounds as a microtubule-interfering agents (MIAs). The new derivatives, because of their potential antimitotic and antiangio-genic activity, can be used as ingredients in the preparations used in the treatment of cancer. |
申请公布号 |
WO2013147629(A1) |
申请公布日期 |
2013.10.03 |
申请号 |
WO2013PL00042 |
申请日期 |
2013.03.28 |
申请人 |
UNIWERSYTET MEDYCZNY IM. KAROLA MARCINKOWSKIEGO |
发明人 |
STEFANSKI, TOMASZ;ROZANSKI, JAKUB;MIKSTACKA, RENATA;SOBIAK, STANISLAW |
分类号 |
C07D233/64;A61K31/10;A61K31/4164;A61K31/421;A61P35/00;C07C323/18;C07C323/62;C07D263/32 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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