A method of preventing drug use relapse by administering an effective amount of an alpha3beta4 nicotinic antagonist to a mammal after an initial period of drug use, and preventing a relapse of drug use. A method of preventing drug use relapse due to cue inducement by administering an effective amount of an alpha3beta4 nicotinic antagonist to a mammal after an initial period of drug use, and preventing a relapse of drug use during cue inducement. A method of preventing drug use relapse due to cue inducement by modulating the dopaminergic mesolimbic pathway by blocking alpha3beta4 nicotinic receptors in the habenulo-interpeduncular pathway and the basolateral amygdala of a mammal after an initial period of drug use, and preventing a relapse of drug use during cue inducement. A method of preventing drug use relapse by preventing a relapse of drug use during cue inducement.
申请公布号
WO2013148572(A1)
申请公布日期
2013.10.03
申请号
WO2013US33703
申请日期
2013.03.25
申请人
ALBANY MEDICAL COLLEGE;GLICK, STANLEY, D.;POLSTON, JAMES, E.