摘要 |
A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid. The tissue thickness compensator may comprise a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and/or pharmaceutically active agent. The encapsulation may comprise a biodegradable material to degrade in vivo and/or in situ. The tissue thickness compensator may comprise a hydrogel. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described. |
申请人 |
ETHICON ENDO-SURGERY, INC. |
发明人 |
BAXTER, III CHESTER O.;SHELTON, IV FREDERICK E.;SCHEIB, CHARLES J.;WIDENHOUSE, CHRISTOPHER W.;WEISENBURGH, II WILLIAM B.;STAMMEN, JOHN L.;RANSICK, MARK H.;MUTCHLER, STEPHANIE A.;KNIGHT, GARY W.;CROPPER, MICHAEL S.;CONLON, SEAN P.;SWAYZE, JEFFREY S. |