发明名称 |
VACCINE FOR TREATMENT OF TAUTOPATHY |
摘要 |
This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a secretion signal sequence, wherein the vaccine is capable of inducing an antibody against an (optionally phospholylated) tau protein in a subject in a more sustained manner compared with a case where the mutant tau protein is administered directly. |
申请公布号 |
EP2522360(A4) |
申请公布日期 |
2013.10.02 |
申请号 |
EP20110731877 |
申请日期 |
2011.01.11 |
申请人 |
KYOTO UNIVERSITY;NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES |
发明人 |
INOUE, HARUHISA;TAKEUCHI, HIROKI;TAKAHASHI, RYOSUKE;HIGUCHI, MAKOTO;JI, BIN;SUHARA, TETSUYA |
分类号 |
A61K39/00;A61K35/76;A61K48/00;A61P25/14;A61P25/22;A61P25/28;C07K14/47 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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