发明名称 |
PROTEINAS RECOMBINANTES CON EFECTO ANTITUMORAL. |
摘要 |
The invention relates to the provision of a recombinant protein comprising ribonuclease activity, which includes a sequence derived from human pancreatic ribonuclease (RNasa-PH) having the sequence SEC ID NO: 37, which is fused by the N-terminal end thereof to a conventional nuclear localization sequence. The invention further relates to a recombinant DNA molecule that codes for said protein, to a vector that includes said DNA molecule and to a cell that includes said vector. The invention additionally relates to a method for producing the recombinant protein and to the use of same as an antitumor agent.
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申请公布号 |
ES2388020(B1) |
申请公布日期 |
2013.10.01 |
申请号 |
ES20110030324 |
申请日期 |
2011.03.10 |
申请人 |
UNIVERSITAT DE GIRONA |
发明人 |
VILANOVA BRUGUES, MARIA;BENITO MUNDET, ANTONI;RIBO PANOSA, MARC;CASTRO GALLEGOS, JESSICA;TUBERT JUHE, PERE;VERT COMPANY, ANNA |
分类号 |
C12N9/22;A61K38/46 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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