| 发明名称 |
Pyrazoloquinolones are potent PARP inhibitors |
| 摘要 |
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
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| 申请公布号 |
US8546368(B2) |
申请公布日期 |
2013.10.01 |
| 申请号 |
US20070675570 |
申请日期 |
2007.02.15 |
| 申请人 |
PENNING THOMAS D.;ZHU GUI-DONG;GANDHI VIRAJKUMAR B.;GONG JIANCHUN;GIRANDA VINCENT L.;ABBVIE INC. |
发明人 |
PENNING THOMAS D.;ZHU GUI-DONG;GANDHI VIRAJKUMAR B.;GONG JIANCHUN;GIRANDA VINCENT L. |
| 分类号 |
A01N43/00;A61K31/33;C07D401/00;C07D413/00 |
主分类号 |
A01N43/00 |
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