发明名称 Substituted bicyclic imidazole derivatives as gamma secretase modulators
摘要 The present invention is concerned with novel substituted bicyclic imidazole derivatives of Formula (I) wherein R0, R1, R3, R4, X, A1, A2, A3, A4, Y1, Y2 and Y3 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said novel compound as an active ingredient as well as the use of said compounds as a medicament.
申请公布号 US8546440(B2) 申请公布日期 2013.10.01
申请号 US200913133027 申请日期 2009.12.16
申请人 GIJSEN HENRICUS JACOBUS MARIA;MACDONALD GREGOR JAMES;BISCHOFF FRANCOIS PAUL;TRESADERN GARY JOHN;TRABANCO-SUAREZ ANDRES AVELINO;VAN BRANDT SVEN FRANCISCUS ANNA;BERTHELOT DIDIER JEAN-CLAUDE;JANSSEN PHARMACEUTICALS, INC. 发明人 GIJSEN HENRICUS JACOBUS MARIA;MACDONALD GREGOR JAMES;BISCHOFF FRANCOIS PAUL;TRESADERN GARY JOHN;TRABANCO-SUAREZ ANDRES AVELINO;VAN BRANDT SVEN FRANCISCUS ANNA;BERTHELOT DIDIER JEAN-CLAUDE
分类号 A61K31/5377;A61K31/4188;A61K31/4196;A61K31/4439;A61K31/506;C07D487/04 主分类号 A61K31/5377
代理机构 代理人
主权项
地址
您可能感兴趣的专利