ALTERNATIVELY SPLICED mRNA ISOFORMS AS PROGNOSTIC INDICATORS FOR METASTATIC CANCER
摘要
<p>The present invention provides a method for identifying a tumor as likely to metastasize, or likely to have metastasized, comprising obtaining a sample of the tumor and quantitating alternatively spliced mRNA isoforms of a cell motility gene, a cell adhesion gene and /or an actin cytoskeletal remodeling gene in the sample, or any specified genes or the level of RNA binding proteins compared to a predetermined non-metastasizing control.</p>
申请公布号
SG192910(A1)
申请公布日期
2013.09.30
申请号
SG20130063789
申请日期
2012.02.24
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY;MONTEFIORE MEDICAL CENTER