PYRIDIN-4-YL)BENZYLAMIDES AS ALLOSTERIC MODULATORS OF ALPHA 7 nAChR
摘要
<p>The present invention relates to (pyridin-4-yl)benzylamides derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulators having the capability to increase the efficacy of nicotinic receptor agonists.</p>
申请公布号
SG192939(A1)
申请公布日期
2013.09.30
申请号
SG20130064225
申请日期
2012.02.23
申请人
JANSSEN PHARMACEUTICA NV
发明人
DE BOECK, BENOIT, CHRISTIAN, ALBERT, GHISLAIN;ROMBOUTS, GEERT;LEENAERTS, JOSEPH, ELISABETH;MACDONALD, GREGOR, JAMES