COMPOSITION FOR PREVENTING OR TREATING IMMUNE DISEASE COMPRISING MYELOID DERIVED SUPPRESSOR CELLS AND REBAMIPIDE

摘要

PURPOSE: A composition for preventing or treating immunization disease including bone marrow-derived suppressor cell and rebamipide effectively treats immunization reaction and inflammation, by reducing the level of an autoimmune antibody and accelerating the activation of immunodulatory T cells. CONSTITUTION: A composition for preventing or treating immunization disease includes bone marrow-derived suppressor cell and rebamipide. The marrow-derived suppressor cell and rebamipide accelerates or increase the activity of Regulatory T cell: Treg and decrease the concentration of IgG, IgG1, and lgG2a in blood. The marrow-derived suppressor cell and rebamipide reduces and suppress the expression of IL-17 which is the inflammatory cytokine. The composition includes 5x10^5-2x10^6 of the marrow-derived suppressor cells.