摘要 |
The present invention relates to novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers including R and S isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions for prophylaxis, amelioration and/or treatment of one or more condition mediated by DPP-IV, in a subject in need thereof, comprising compounds of formula I, methods for prophylaxis, amelioration and/or treatment of one or more condition mediated by DPP-IV, methods for prophylaxis, amelioration and/or treatment of diabetes and the use of compounds of Formula I. |