发明名称 SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS
摘要 In one aspect, the invention relates to compounds having the formula: (I) where R1-R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
申请公布号 SG192815(A1) 申请公布日期 2013.09.30
申请号 SG20130062401 申请日期 2012.02.16
申请人 THERAVANCE, INC. 发明人 FLEURY, MELISSA;GENDRON, ROLAND;HUGHES, ADAM D.
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