| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to pharmaceutical industry and represents applied for cosmetic or therapeutic purposes water composition in form of gel, based on hyaluronic acid or one of its salts, one or several polyols and lidocaine, subjected to thermal sterilisation, which results in its improved viscoelastic rheological properties and improved persistence in vivo, in which concentration of hyaluronic acid or one of its salts constitutes from 0.01 mg/ml to 100 mg/ml, molecular weight of hyaluronic acid or one of its salts constitutes from 1000 Dalton to 10×10Dalton, polyol concentration constitutes from 0.0001 to 100 mg/ml, and concentration of lidocaine constitutes from 0.0001 to 50 mg/ml.EFFECT: invention ensures increase of physical-chemical stability of gels, based on hyaluronic acid, in order to increase duration of impact effect.13 cl, 5 ex |
