LYOPHILIZATION METHODS, COMPOSITIONS, AND KITS

摘要

600271 Describes a method of lyophilizing an active ingredient, being Antithrombin (AT III) and crystallising agent selected from alanine, mannitol, glycine or sodium chloride, wherein the method involves exposing the composition to a first temperature for a first period of time sufficient to obtain a first composition having at least one crystallizing excipient partially or completely crystallized.