发明名称 STABILIZATION METHOD OF RAMALIN USING POROUS MATRIX AND STABILIZED RAMALIN SOLUTION
摘要 PURPOSE: A stabilizing method of ramalin is provided to maintain titer in high level and to store ramalin with excellent anti-oxidation and anti-inflammation effect. CONSTITUTION: A stabilizing method of ramalin represented by chemical formula 1 comprises a step of absorbing the ramalin to a hydrophilic porous matrix; a step of reforming the surface of a porous matrix on which the ramalin is absorbed to a hydrophilic surface; and a step of dispersing the porous matrix into an organic solvent. The hydrophilic porous matrix consists of hydrophilic aerogel. The organic solvent is selected from caprylic/capric triglyceride, squalane, silicone oil, mineral oil, vegetable oil, and a mixture thereof.
申请公布号 KR20130106045(A) 申请公布日期 2013.09.27
申请号 KR20120027649 申请日期 2012.03.19
申请人 KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY 发明人 YIM, JOUNG HAN;KIM, IL CHAN;KIM, DOC KYU;HAN, SE JONG;LEE, HYOUNG SEOK;HARI DATTA BHATTARAI;PARK, SU JIN
分类号 C07C241/04;A61K31/135;A61Q19/02;C07C243/22 主分类号 C07C241/04
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