发明名称 ADJUVANTS
摘要 <p>The invention provides a hydroxy double salt for use in modulating an immune response to an antigen. The hydroxy double salt is of formula (I): [Ma(OH)b]x+(An-)x/n in which M is a divalent metal cation or a mixture of two or more divalent metal cations; A is an interlayer anion, which is not OH-, having a charge n;a is a number greater than zero; b is a number greater than zero that is less than 2a; and x is a number greater than zero; wherein optionally some or all of the interlayer anion A may be replaced by one or more biologically active agent and/or one or more antigen. The hydroxy double salt may, for example, be used for preventing or treating a medical condition selected from infectious diseases; allergies and other immune-related sensitivities; autoimmune diseases; transplantation reactions; proliferative diseases; and other inflammatory conditions.</p>
申请公布号 WO2013140136(A1) 申请公布日期 2013.09.26
申请号 WO2013GB50636 申请日期 2013.03.14
申请人 ISIS INNOVATION LTD 发明人 AUSTYN, JONATHAN MARK;O'HARE, DERMOT;WILLIAMS, GARETH RICHARD
分类号 A61K39/39 主分类号 A61K39/39
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