发明名称 SALTS OF PRODRUGS OF PIPERAZINE AND SUBSTITUTED PIPERIDINE ANTIVIRAL AGENTS
摘要 This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. wherein: X is C or N with the proviso that when X is N, R1 does not exist; W is C or N with the proviso that when W is N, R2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. wherein: L and M are independently selected from the group consisting of C1-C6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.
申请公布号 US2013253196(A1) 申请公布日期 2013.09.26
申请号 US201313861804 申请日期 2013.04.12
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 UEDA YASUTSUGU;CONNOLLY TIMOTHY P.;KADOW JOHN F.;MEANWELL NICHOLAS A.;WANG TAO;CHEN CHUNG-PIN H.;YEUNG KAP-SUN;ZHANG ZHONGXING;LEAHY DAVID KENNETH;PACK SHAWN K.;SOUNDARARAJAN NACHIMUTHU;SIRARD PIERRE;LEVESQUE KATHIA;THORAVAL DOMINIQUE
分类号 C07F9/6561;A61K31/437;A61K31/496;A61K31/675;C07D471/04;C07F9/09;C07F9/572 主分类号 C07F9/6561
代理机构 代理人
主权项
地址
您可能感兴趣的专利