A METHOD AND A KIT FOR THE DETECTION OF ANTI-BETA AMYLOID ANTIBODIES

摘要

An in vitro method and a kit for the quantification of antibodies anti- beta amyloid protein in a sample of cerebrospinal fluid comprising the following steps: a) concentrating the quantity of said antibodies of said sample with magnetic micro beads coated with macromolecules capable of binding said antibodies; b) analysing the concentrated sample obtained in step a) by immunoenzyme assay or by radioimmunoassay; c) analysing a sample comprising antibodies anti-beta amyloid protein having a known titre with the same assay used in step b) and elaborating the related calibration curve, wherein said antibody having a known titre is a murine antibody belonging to the lgG2a or lgG2b class or a human or humanized antibody belonging to the lgG2b or lgGi class.