METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGINOSIS OF PANCREATIC CANCER

摘要

The invention provides methods, compositions and kits for the detection and treatment of pancreatic cancer. In certain embodiments the invention provides a method of detecting pancreatic cancer in a subject comprising a) obtaining a sample from a subject; b) contacting the sample obtained from the subject with one or more agents that detect one or more markers expressed by a pancreatic cancer cell c) contacting a non-cancerous cell with the one or more agents from b); and d) comparing the expression level of the marker in the sample obtained from the subject with the expression level in the non-cancerous cell, wherein a higher level of expression of the marker in the sample compared to the non-cancerous cell indicates that the subject has pancreatic cancer. Suitable markers include the genes encoded for by any of the genes disclosed infra.