发明名称 |
ORAMUCOSAL PHARMACEUTICAL DOSAGE FORM |
摘要 |
This invention relates to an oramucosal pharmaceutical dosage form in the form of a wafer. The wafer comprises a porous, hydroscopic, muco-adhesive polymeric matrix with at least one desired pharmaceutically active compound added thereto. The polymer is selected from a number of polymers having different dissolution rates and, in use when taken orally, the matrix adheres to an oramucosal surface to dissolve over a predetermined period of time to release the pharmaceutically active compound. The invention also extends to a method of manufacturing an oramucosal pharmaceutical dosage form in the form of a wafer which involves freeze drying or lyophilisation.
|
申请公布号 |
US2013252916(A1) |
申请公布日期 |
2013.09.26 |
申请号 |
US201313736176 |
申请日期 |
2013.01.08 |
申请人 |
JOHANNESBURG UNIVERSITY OF THE WITWATERSRAND,;UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG |
发明人 |
PATEL RUPAL;PILLAY VINESS;DANCKWERTS MICHAEL PAUL |
分类号 |
A61K9/00;A61K47/38 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|