PATHOGEN DETECTION USING METAL ENHANCED FLUORESCENCE

摘要

Pathogen sensors, systems for pathogen detection, peptide ligands, and methods for detecting pathogens are disclosed. The pathogen sensors include silver particles attached to optically clear substrates, immobilized capture peptide or glycan ligands attached to the silver particles, and free labeling peptide or glycan ligands having fluorophores. Binding of the immobilized capture ligands and the free labeling ligands to the pathogen positions the fluorophore at a distance from the silver particles sufficient to initiate metal enhanced fluorescence.