| 摘要 |
<p>A method for detecting and/or monitoring a chronic inflammation condition associated with rheumatoid arthritis. The method comprises the steps of: (i) collecting a sample; (ii) detecting in the sample, one or more of a HMGNl protein, a LCP-1 protein, a prtn3 protein, a sec22b protein, and a PYGL glycogen phosphorylase protein thereby producing a result; and (iii) correlating the result with a control. A test kit for diagnosing or monitoring a chronic inflammatory condition associated with rheumatoid arthritis. The test kit comprises an antibody for complexing with one of a HMGNl protein, a LCP-1 protein, a prtn3 protein, a sec22b protein, and a PYGL glycogen phosphorylase protein. A composition for treatment of a chronic inflammation condition associated with rheumatoid arthritis, comprising a therapeutically effective amount of an exogenous agonist for decreasing cellular production of one or more of a HMGNl protein, a LCP-1 protein, a prtn3 protein, a sec22b protein, and a PYGL glycogen phosphorylase protein.</p> |
