Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide

摘要

[Problem] To provide a production method by which a glycopeptide having a desired sialyl sugar chain can be obtained with high yield without decomposing sialic acid at a non-reducing terminal of a sugar chain when the glycopeptide is synthesized by a Boc solid phase synthesis method. [Solution] This method for producing a glycopeptide having a sialyl sugar chain is characterized in that a carboxyl group of sialic acid at a non-reducing terminal of a sugar chain is protected with a phenacyl group in a Boc-sialyl sugar chain-added amino acid derivative that is used in a Boc solid phase synthesis method.