发明名称 |
COMPOSITIONS CONTAINING PURINE NUCLEOSIDES AND MANGANESE AND THEIR USES |
摘要 |
This invention encompasses methods of preserving protein function by contacting a protein with a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese). In addition, the invention encompasses methods of treating and/or preventing a side effect of radiation exposure and methods of preventing a side effect of radiotherapy comprising administration of a pharmaceutically effective amount of a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e g., manganese) to a subject in need thereof. The compositions may comprise D. radiodurans extracts. |
申请公布号 |
EP2187894(A4) |
申请公布日期 |
2013.09.25 |
申请号 |
EP20080835075 |
申请日期 |
2008.08.18 |
申请人 |
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES |
发明人 |
DALY, MICHAEL, J.;GAIDAMAKOVA, ELENA, K.;MATROSOVA, VERA K.;LEVINE, RODNEY L.;WEHR, NANCY B. |
分类号 |
A61K31/7076;A61K8/24;A61K8/44;A61K8/60;A61K8/99;A61K33/32;A61K35/74;A61K45/06;A61P39/00;A61Q17/00;A61Q17/04 |
主分类号 |
A61K31/7076 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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