发明名称 |
INDUCTION OF alpha-HELIX CONFORMATIONS IN PROTEINS AND PEPTIDES |
摘要 |
<p>Substituted tricyclic diproline analogues of the formula (I): wherein the variables are as defined herein. Also disclosed are methods for the production thereof, the use thereof for the induction of an alpha-helix conformation in peptides and/or proteins, pharmaceuticals containing said compounds, methods for the production of a peptide library containing said compounds, and peptide libraries containing said compounds.</p> |
申请公布号 |
EP2451815(B1) |
申请公布日期 |
2013.09.25 |
申请号 |
EP20100740516 |
申请日期 |
2010.07.09 |
申请人 |
UNIVERSITAET ZU KOELN;FORSCHUNGSVERBUND BERLIN E.V. |
发明人 |
SCHMALZ, HANS-GUENTHER;KUHNE, RONALD;HACK, VERENA;REUTER, CEDRIC |
分类号 |
C07D487/18;A61K31/407;A61P25/28;A61P31/00;A61P35/00 |
主分类号 |
C07D487/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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