摘要 |
The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: (see formula 1) wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from -N= etc., Y3 and Y4 are selected from -CH= etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.
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申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;SAKAI, TOSHIYUKI |
发明人 |
IIKURA, HITOSHI;HYOUDOH, IKUMI;AOKI, TOSHIHIRO;FURUICHI, NORIYUKI;MATSUSHITA, MASAYUKI;WATANABE, FUMIO;OZAWA, SAWAKO;SAKAITANI, MASAHIRO;HO, PIL-SU;TOMII, YASUSHI;TAKANASHI, KENJI;HARADA, NAOKI |