发明名称 |
PIPERIDINE AND AZETIDINE DERIVATIVES AS GLYT1 INHIBITORS |
摘要 |
The present invention provides compounds of formula (I), wherein both p's are one or two, R1 is generally heteroaryl or cycloalkyl, R2 is C3-6cycloalkyl or phenyl and R3 is heteroaryl, and pharmaceutically acceptable salts thereof, as GlyT1 inhibitors for treating schizophrenia, pharmaceutical compositions comprising the same and methods for their preparation.
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申请公布号 |
CA2592345(C) |
申请公布日期 |
2013.09.24 |
申请号 |
CA20052592345 |
申请日期 |
2005.12.21 |
申请人 |
MERCK SHARP & DOHME LIMITED |
发明人 |
BLACKABY, WESLEY PETER;FLETCHER, STEPHEN ROBERT;JENNINGS, ANDREW;LEWIS, RICHARD THOMAS;NAYLOR, ELIZABETH MARY;STREET, LESLIE JOSEPH;THOMSON, JOANNE |
分类号 |
A61K31/4545;A61K31/4155;A61K31/4178;A61K31/4192;A61K31/4436;A61K31/4439;A61K31/454;A61P25/18;C07D401/12;C07D401/14;C07D403/12;C07D409/14 |
主分类号 |
A61K31/4545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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