发明名称 PIPERIDINE AND AZETIDINE DERIVATIVES AS GLYT1 INHIBITORS
摘要 The present invention provides compounds of formula (I), wherein both p's are one or two, R1 is generally heteroaryl or cycloalkyl, R2 is C3-6cycloalkyl or phenyl and R3 is heteroaryl, and pharmaceutically acceptable salts thereof, as GlyT1 inhibitors for treating schizophrenia, pharmaceutical compositions comprising the same and methods for their preparation.
申请公布号 CA2592345(C) 申请公布日期 2013.09.24
申请号 CA20052592345 申请日期 2005.12.21
申请人 MERCK SHARP & DOHME LIMITED 发明人 BLACKABY, WESLEY PETER;FLETCHER, STEPHEN ROBERT;JENNINGS, ANDREW;LEWIS, RICHARD THOMAS;NAYLOR, ELIZABETH MARY;STREET, LESLIE JOSEPH;THOMSON, JOANNE
分类号 A61K31/4545;A61K31/4155;A61K31/4178;A61K31/4192;A61K31/4436;A61K31/4439;A61K31/454;A61P25/18;C07D401/12;C07D401/14;C07D403/12;C07D409/14 主分类号 A61K31/4545
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