There are provided compounds of the formula wherein X, Y, Z, R1, R2, R3 and R4 are as described herein and enantiomers and pharmaceutically acceptable salts and esters thereof. The compounds are useful as anticancer agents.
申请公布号
US2013244958(A1)
申请公布日期
2013.09.19
申请号
US201313785267
申请日期
2013.03.05
申请人
HOFFMANN-LA ROCHE INC.
发明人
BARTKOVITZ DAVID JOSEPH;CHU XIN-JIE;VU BINH THANH;ZHAO CHUNLIN;FISHLOCK DANIEL