| 摘要 |
insulin Sensitive Insulin Resistant e.g., Muscle, liver *>P13K rn"t-Msee 0.9, uscelivr P K 0 .9., Muscle, liverA insulin PKC - IRS,,,o GSK31acilo N GSK 3 cuv GLUT4 L I G l 'cG L U 4 7Uptake M A GS NFkB-p65 SREBPic GS NFkB-p65 SREBPic Glycogen Storage +TNFa SCD1 FAS ACC olL6 + Mal-CoA Lipid Storagg, 1 p-oxidation Botanical compounds to modulate kinase activity are disclosed. The compounds and methods disclosed also inhibit expression of COX-2, inhibit synthesis o prostaglandins selectively in target cells, and inhibit inflammatory response selectively. The compositions contain at least one fraction isolated or derived from hops or Acacia. |
