发明名称 |
BIS-QUARTERNARY CINCHONA ALKALOID SALTS AS ASYMMETRIC PHASE TRANSFER CATALYSTS |
摘要 |
<p>The invention is directed to novel bis-quarternary cinchona alkaloid salts and the use of bis-quarternary cinchona alkaloid salts in asymmetric phase transfer catalysis. The present invention is directed to novel bis-quarternary cinchona alkaloid salts and the use of bis-quartenary cinchona alkaloid salts in asymmetric phase transfer catalysis. On certain substrates and under specific reaction conditions, the inventors have discovered that the use of bis-quarternary cinchona alkaloid salts in asymmetric phase transfer catalysis surprisingly provides for a more active and efficient process as compared to mono-quarternary catalysts.</p> |
申请公布号 |
CA2865941(A1) |
申请公布日期 |
2013.09.19 |
申请号 |
CA20132865941 |
申请日期 |
2013.03.13 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
XIANG, BANGPING;YASUDA, NOBUYOSHI |
分类号 |
C07D453/04;B01J31/02;C07B53/00;C07D207/38 |
主分类号 |
C07D453/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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