| 发明名称 |
CYCLIC UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 |
| 摘要 |
This invention relates to novel compounds of the Formula (I), (Ia) and (Ib), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, j which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 beta-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell Or the inhibition of the conversion of cortisone to Cortisol in a cell.
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| 申请公布号 |
US2013245051(A1) |
申请公布日期 |
2013.09.19 |
| 申请号 |
US201313873574 |
申请日期 |
2013.04.30 |
| 申请人 |
CLAREMON DAVID A.;ZHUANG LINGHANG;TICE COLIN M.;YE YUANJIE;HE WEI;SINGH SURESH B.;XU ZHENRONG;CACATIAN SALVACION;ZHAO WEI;VITAE PHARMACEUTICALS, INC. |
发明人 |
CLAREMON DAVID A.;ZHUANG LINGHANG;TICE COLIN M.;YE YUANJIE;HE WEI;SINGH SURESH B.;XU ZHENRONG;CACATIAN SALVACION;ZHAO WEI |
| 分类号 |
C07D239/10 |
主分类号 |
C07D239/10 |
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