发明名称 |
USE OF CONKUNITZIN-S1 FOR THE MODULATION OF GLUCOSE-INDUCED INSULIN SECRETION |
摘要 |
The present invention relates to a (poly)peptide or a peptidomimetic thereof having the biological activity of Conkunitzin-S1, wherein said (poly)peptide is selected from (a) a polypeptide comprising or having the amino acid sequence of SEQ ID NO: 1; (b) a polypeptide having at least 85% sequence identity to SEQ ID NO:1; or (c) a fragment of a) or b); wherein said (poly)peptide or peptidomimetic specifically modulates the activity of a channel having the activity of a Kv1.7 containing channel, for the treatment or prevention of metabolic diseases or conditions, or secondary diseases or conditions related to said metabolic diseases or conditions.
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申请公布号 |
US2013244933(A1) |
申请公布日期 |
2013.09.19 |
申请号 |
US201313858241 |
申请日期 |
2013.04.08 |
申请人 |
WISSENSCHAFTEN E.V. MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER;UNIVERSITAT ZU LUBECK;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
TERLAU HEINRICH;FINOL-URDANETA ROCIO;BECKER STEFAN;RAASCH WALTER |
分类号 |
C07K14/435 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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