发明名称 |
ACRYLOMIDO DERIVATIVES USEFUL AS INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION |
摘要 |
Acrylamido derivatives useful as therapeutic agents, particularly for the prevention and/or treatment of diseases and conditions associated with the activity of the mitochondrial permeability transition pore (MPTP), such as the diseases characterized by ischemia/reperfusion, oxidative or degenerative tissue damage, are herein described. These compounds belong to the structural formula (I) wherein R, R', R'', W and a are as defined in the specification. The invention also relates to the preparation of these compounds, as well as to pharmaceutical compositions comprising them.
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申请公布号 |
US2013245019(A1) |
申请公布日期 |
2013.09.19 |
申请号 |
US201313874081 |
申请日期 |
2013.04.30 |
申请人 |
FANCELLI DANIELE;VARASI MARIO;PLYTE SIMON;BALLARINI MARCO;CAPPA ANNA;CARENZI GIACOMO;MINUCCI SAVERIO;PAIN GILLES;VILLA MANUELA;CONGENIA SRL |
发明人 |
FANCELLI DANIELE;VARASI MARIO;PLYTE SIMON;BALLARINI MARCO;CAPPA ANNA;CARENZI GIACOMO;MINUCCI SAVERIO;PAIN GILLES;VILLA MANUELA |
分类号 |
C07C235/38;C07C323/41;C07D209/08;C07D211/22;C07D213/30;C07D213/36;C07D213/68;C07D231/56;C07D233/64;C07D235/06;C07D235/30;C07D239/47;C07D249/18;C07D263/32;C07D263/56;C07D295/096;C07D295/135 |
主分类号 |
C07C235/38 |
代理机构 |
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代理人 |
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