发明名称 BATCHES OF RECOMBINANT ADENOVIRUS WITH ALTERED TERMINAL ENDS
摘要 <p>The invention provides a composition comprising a plurality of recombinant adenovirus particles, being a recombinant human adenovirus of serotype 5, 26, 34, 35, 48,49 or 50, or a recombinant simian adenovirus, characterized in that the genomes of essentially all adenovirus particles in said composition comprise as the 5' terminal nucleotides the nucleotide sequence: CTATCTAT. The invention also provides methods to produce such compositions.</p>
申请公布号 WO2013135615(A1) 申请公布日期 2013.09.19
申请号 WO2013EP54846 申请日期 2013.03.11
申请人 CRUCELL HOLLAND B.V. 发明人 CUSTERS, JEROME H.H.V.;VELLINGA, JORT
分类号 C12N7/02;C12N7/00;C12N15/86;C12N15/861 主分类号 C12N7/02
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