发明名称 SOLID DISPERSION IMPROVING ABSORPTION PERFORMANCE AND PREPARATION OF SAME
摘要 <p>Provided are a solid dispersion improving absorption performance and a method for preparing same. Specifically, a solid dispersion is provided, comprising (A): a compound of Formula A as an active ingredient or a derivant thereof, or a pharmaceutically acceptable salt, a hydrate or a solvate thereof; and (B): a hydrophilic high polymer carrier. A weight ratio of (A) to (B) ranges from 1:1 to 1:40. The solid dispersion according to the present invention can significantly improve a vitro dissolution of the active ingredient and remarkably improve absorption of a mammal for the active ingredient, thereby effectively reducing the dosage thereof in use.</p>
申请公布号 WO2013135189(A1) 申请公布日期 2013.09.19
申请号 WO2013CN72645 申请日期 2013.03.14
申请人 SUZHOU ZELGEN BIOPHARMACEUTICALS CO., LTD. 发明人 YI, BIHUI;SHANG, XIAOFANG;LU, HUIPING;SHENG, ZELIN
分类号 A61K9/14;A61K31/44;A61K47/32;A61P35/00 主分类号 A61K9/14
代理机构 代理人
主权项
地址