发明名称 |
Bi-and polycyclic substituted isoquinoline and isoquinoline derivatives as rho kinase inhibitors |
摘要 |
<p>The invention relates to bi- and polycyclic substituted isoquinoline and isoquinolinones of the formula (I) wherein R1 to R12 are as defined in the application useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.</p> |
申请公布号 |
EP2303845(B1) |
申请公布日期 |
2013.09.18 |
申请号 |
EP20090768941 |
申请日期 |
2009.06.18 |
申请人 |
SANOFI |
发明人 |
PLETTENBURG, OLIVER;LORENZ, KATRIN;LOEHN, MATTHIAS;DUCLOS, OLIVIER;BISCARRAT, SANDRINE |
分类号 |
C07D217/24;A61K31/472;A61P9/00;A61P25/00;A61P27/00;A61P37/00;C07D493/08;C07D495/08 |
主分类号 |
C07D217/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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