发明名称 |
PROCESS FOR PRODUCTION OF POLYPEPTIDES |
摘要 |
Vectors for producing polypeptides heterologous to prokaryotes are described comprising, along with the polypeptide-encoding nucleic acid, anti-termination nucleic acid that inhibits intragenic transcription termination with a non-lambda promoter therefor and/or nucleic acid encoding a GreA or GreB protein and a promoter therefor. Also described are processes for producing a heterologous polypeptide in prokaryotic host cells utilizing such elements to improve the quality and/or quantity of heterologous polypeptide produced.
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申请公布号 |
CA2438074(C) |
申请公布日期 |
2013.09.17 |
申请号 |
CA20022438074 |
申请日期 |
2002.02.22 |
申请人 |
GENENTECH, INC. |
发明人 |
PAEGLE, ERIKS SASHA;REILLY, DOROTHEA;YANSURA, DANIEL G. |
分类号 |
C12N15/09;C12N15/70;C07K14/245;C12N15/12;C12N15/19;C12N15/71;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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