| 发明名称 |
PYRAZOLO[1,5-A]PYRIMIDINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE |
| 摘要 |
<p>Pyrazolo[1,5-a]pyrimidine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.</p> |
| 申请公布号 |
CA2866143(A1) |
申请公布日期 |
2013.09.12 |
| 申请号 |
CA20132866143 |
申请日期 |
2013.03.05 |
| 申请人 |
LEXICON PHARMACEUTICALS, INC. |
发明人 |
BI, YINGZHI;CARSON, KENNETH GORDON;CIANCHETTA, GIOVANNI;GREEN, MICHAEL ALAN;KUMI, GODWIN;MAIN, ALAN;ZHANG, YULIAN;ZIPP, GLENN GREGORY |
| 分类号 |
C07D487/04;A61K31/519;A61P25/16;A61P25/18;A61P25/28 |
主分类号 |
C07D487/04 |
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