Hepcidin and Hepcidin Antibodies

摘要

The invention relates to purified, correctly folded hepcidin, antibodies that bind hepcidin, and methods of making and using such materials. Also provided are methods of treated hepcidin-related disorders. WO 2008/097461 PCT/US2008/001325 Day: 0 3 3+2hr Ab (sc) IP harvest B 25 pg hepcidin * P < 0.05 ** P <0.01 =saline n=5 =160 n=5 .-lhepcidin + isotype control 140 -*ihepcidin + Ab 2.7 (110pM) 0)100 Ab dosing (mg/mouse) Fig. 11