发明名称 |
Methods for determining hepatocellular carcinoma subtype and detecting hepatic cancer stem cells |
摘要 |
The invention provides a method of determining an HCC subtype in a subject comprising a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. The invention further provides methods of detecting HCC stem cells in a sample. Additionally, the invention provides methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells. |
申请公布号 |
AU2008262252(B2) |
申请公布日期 |
2013.09.12 |
申请号 |
AU20080262252 |
申请日期 |
2008.06.09 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES;THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION |
发明人 |
YAMASHITA, TARO;WANG, XIN WEI;CROCE, CARLO M.;JI, JUNFANG |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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