发明名称 |
USE OF LEUKOTRIENE B4 IN COMBINATION WITH A TOLL-LIKE RECEPTOR LIGAND, A RIG-I-LIKE RECEPTOR LIGAND, OR A NOD-LIKE RECEPTOR LIGAND TO ENHANCE THE INNATE IMMUNE RESPONSE |
摘要 |
The present invention relates to the use of leukotriene B4 to enhance the response of Toll-like receptor (TLR), RIG-I-like receptor (RLR), and NOD-like receptor (NLR) when stimulated simultaneously with respective proper ligands. The use in combination of LTB4 with those ligands is useful to potentiate immune response for the treatment of autoimmune diseases, immunosuppressive diseases, as well as immunological disorders.
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申请公布号 |
US2013236496(A1) |
申请公布日期 |
2013.09.12 |
申请号 |
US201113807020 |
申请日期 |
2011.06.20 |
申请人 |
GOSSELIN JEAN;GAUDREAULT ERIC;UNIVERSITE DE LAVAL |
发明人 |
GOSSELIN JEAN;GAUDREAULT ERIC |
分类号 |
A61K31/557;A61K31/7032;A61K31/7125;A61K31/713;A61K31/739;A61K38/08;A61K38/14;A61K38/17 |
主分类号 |
A61K31/557 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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