发明名称 |
NANOPARTICLES PRODUCED FROM RECOMBINANT POLYMERS AND METHODS OF MAKING AND USING THE SAME |
摘要 |
Described herein are nanoparticles produced from recombinant polymers. The nanoparticles are substantially uniform in size, which provides numerous advantages with respect to the delivery of bioactive agents to a subject. Methods for making the nanoparticles are also described herein. In one aspect, the nanoparticles are produced by the method comprising: a. providing a solution comprising one or more recombinant polymer in a solvent; b. forming droplets comprising the one or more recombinant polymers and the solvent; c. removing the solvent to produce the nanoparticles; and d. separating the nanoparticles based on size to produce nanoparticles that are substantially uniform in size. Finally, pharmaceutical compositions composed of the nanoparticles and methods of using the same are also described.
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申请公布号 |
US2013236396(A1) |
申请公布日期 |
2013.09.12 |
申请号 |
US201113695827 |
申请日期 |
2011.05.03 |
申请人 |
PEASE, III LEONARD FRANKLIN;GHANDEHARI HAMID;ANUMOLU RAJASEKHAR;UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
PEASE, III LEONARD FRANKLIN;GHANDEHARI HAMID;ANUMOLU RAJASEKHAR |
分类号 |
A61K47/42 |
主分类号 |
A61K47/42 |
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