发明名称 METHOD FOR DETECTING INFLAMMATORY BOWEL DISEASE, AND METHOD FOR TESTING HUMAN SALIVARY FLORA
摘要 Provided are a method for detecting inflammatory bowel disease and a method for testing human salivary flora, whereby it is possible to conduct an accurate pathological evaluation with a simple test. The base sequences of 16S ribosomal RNA genes from flora in a saliva sample taken from a test subject are determined at random to obtain a base sequence data set, and salivary analytes associated with inflammatory bowel disease are detected on the basis of the obtained base sequence data set. In such cases, it is preferable to use indices such as: the number of bacterial strains constituting the salivary flora, determined on the basis of the data set; the number of cluster groups based on the similarity between the base sequences included in the data set; the similarity distance between the group and a group of healthy subjects, determined on the basis of the data set; and the abundance of bacteria belonging to specific phyla, genera and species among the salivary flora, determined on the basis of the data set.
申请公布号 WO2013133298(A1) 申请公布日期 2013.09.12
申请号 WO2013JP56077 申请日期 2013.03.06
申请人 THE UNIVERSITY OF TOKYO;SCHOOL CORPORATION, AZABU VETERINARY MEDICINE EDUCATIONAL INSTITUTION;SCHOOL JURIDICAL PERSON KITASATO INSTITUTE;UNIVERSITY OF THE RYUKYUS 发明人 HATTORI MASAHIRA;MORITA HIDETOSHI;OOTA HIROKI;CHINEN HIROSHI
分类号 C12Q1/68;C12N15/09 主分类号 C12Q1/68
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