发明名称 |
MULTISPECIFIC ANTIGEN BINDING PROTEINS TARGETING HGF |
摘要 |
The invention relates to combinations of HGF-antagonists with VEGF antagonists, and provides antigen-binding proteins which bind to HGF comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding protein has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
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申请公布号 |
US2013236467(A1) |
申请公布日期 |
2013.09.12 |
申请号 |
US201113988375 |
申请日期 |
2011.11.23 |
申请人 |
GRIGGS JEREMY;PARMAR RADHA SHAH;STEWARD MICHAEL |
发明人 |
GRIGGS JEREMY;PARMAR RADHA SHAH;STEWARD MICHAEL |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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