Polymorphic forms of bosentan

摘要

Novel polymorphic forms of bosentan and processes for their preparation are disclosed. Further, pharmaceutical compositions comprising said polymorphicforms and the use of said compositions in the treatment of patientssuffering from endothelin receptor mediated disorders, for example,cardiovascular disorders such as hypertension, pulmonary hypertension, ischemia, vasospasm and angina pectoris are disclosed.