发明名称 |
ACCORDION PILL COMPRISING LEVODOPA FOR AN IMPROVED TREATMENT OF PARKINSON'S DISEASE SYMPTOMS |
摘要 |
The invention provides for the use of an accordion pill comprising levodopa for the treatment of symptoms of Parkinson's disease in a subject in need thereof over a 24 hour period, to be administered to the subject in a twice daily administration regimen, with an interval of about 8 to about 10 hours between the first dose and the second dose, and with an interval of about 14 to about 16 hours between the second dose and the first dose of the following day. The twice daily administration regimen provides a stable blood plasma level of levodopa in the subject after multiple administrations and is effective in treating the symptoms of Parkinson's disease over a 24 hour period. |
申请公布号 |
EP2635272(A1) |
申请公布日期 |
2013.09.11 |
申请号 |
EP20110805936 |
申请日期 |
2011.11.01 |
申请人 |
INTEC PHARMA LTD. |
发明人 |
NAVON, NADAV;KIRMAYER, DAVID;SHVETZ, JULIA;KLUEV, ELENA;ABRAMOV, EVA;WEISS, ZEEV;CARNI, GIORA |
分类号 |
A61K31/198;A61K9/00;A61P25/16 |
主分类号 |
A61K31/198 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|