发明名称 HETEROCYCLIC COMPOUNDS AS S1P1 AGONISTS FOR THE TREATMENT OF AUTOIMMUNE AND VASCULAR DISEASES
摘要 <p>Disclosed are compounds of Formula (I) or stereoisomers, salts, or prodrugs thereof, wherein: W is CH2 or O; Q is Formula (II), Formula (III) or Formula (IV); and R1, R2, R3, R4, n, and G are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.</p>
申请公布号 EP2635573(A1) 申请公布日期 2013.09.11
申请号 EP20110782723 申请日期 2011.11.02
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 CHERNEY, ROBERT J.;WANG, ZHONGYU
分类号 C07D413/04;A61K31/4245;A61K31/4453;A61P9/00;A61P37/00;C07D413/14 主分类号 C07D413/04
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