发明名称 |
UPCONVERSION OF LIGHT FOR USE IN OPTOGENETIC METHODS |
摘要 |
Provided herein are compositions comprising lanthanide-doped nanoparticles which upconvert electromagnetic radiation from infrared or near infrared wavelengths into the visible light spectrum. Also provided herein are methods activating light-responsive opsin proteins expressed on plasma membranes of neurons and selectively altering the membrane polarization state of the neurons using the light delivered by the lanthanide-doped nanoparticles. |
申请公布号 |
EP2635341(A1) |
申请公布日期 |
2013.09.11 |
申请号 |
EP20110838859 |
申请日期 |
2011.11.04 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
DEISSEROTH, KARL;ANIKEEVA, POLINA |
分类号 |
A61M37/00;A61K41/00;A61K48/00;A61N5/06;B82Y5/00 |
主分类号 |
A61M37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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