ANTITUBERCULOUS COMPOSITION OF ISONIASIDE, ANTITUBERCULOUS COMPOSITION, ANTITUBERCULOUS REMEDY, ANTITUBERCULOUS PREPARATION, AND METHODS FOR PRODUCING IT

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine and pharmaceutical engineering, and concerns a combined antituberculous remedy containing isonicotinic acid hydrazide (isoniaside) and 2-benzylbenzimidazole (dibazol), and a polymer carrier that is an interpolymer complex of poly(meth)acrylic acid and polyethylene glycol, as well as a method for preparing it.EFFECT: antituberculous remedy according to the invention has bacteriostatic and bactericidal action on tuberculosis mycobacteria; it provides the continuous maintainance of the active substance concentration at the therapeutically effective level; it causes no considerable blood variations; it is 2,5 times less toxic than isoniaside, and 10 times more active than isoniaside.7 cl, 1 dwg, 11 tbl, 16 ex